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Empirical Finance
创建日期：2024-09-06 14:55:20
所属分类：金融Finance
标签： Finance
Empirical Finance

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Empirical Finance 


Here are five small-cap bio stocks, with tickers PLX, EYEN, SPRY, OTLK, VTGN. Each of these bio companies has either experienced a PDUFA event or released phase 3 results within the past year.

Although certain PDUFA decisions are endorsed by the FDA, there are instances where their associated share prices barely go up after the announcement but rather undergo a decline post-decision.  Conversely, some companies witness a significant surge in their stock prices following FDA acceptance (as seen in the case of KALA in December 2022).  Occasionally, positive Phase 3 trial results caused share prices to skyrocket (see, VTGN). Nevertheless, in nearly every instance, unfavorable PDUFA decisions led to a notable decrease in share prices (see, OTLK). These examples shed light on certain dynamics within the small-cap bio stock market, appearing somewhat random at first glance.  However, upon closer examination, one must question whether this randomness is truly the prevailing pattern.

The objective of this assignment is to undertake a comprehensive case study on small-cap bio stocks and develop a robust investment strategy.

First, it is imperative to collect existing cases (the more the better) and analyze summary statistics. To accomplish this, you’ll gather numerous instances of PDUFA decisions and analyze the corresponding movements in share prices.  Subsequently, summarize the percent- age of price increases on average upon approval compared to the opposite trend (price drop when rejected).  This analysis should investigate whether the  “sell the news” phenomenon is evident or if other contributing factors are in play. For instance, it is essential to consider variables such as the time required to bring a product to market and the potential for the company to issue more stocks (public ofering), which could result in a decline in share prices despite positive news.  The maximum points allocated to this part of the presentation is 120. I will assess the comprehensiveness of the summary regarding stylized facts in your analysis.

Secondly, it’s crucial to develop a convincing investment strategy.  One relatively safer ap- proach would involve selling just before the news to capitalize on the pre-announcement drift and avoid exposure to the “sell-the-news” phenomenon.  However, this strategy means missing out on potential gains if there’s a significant price surge, despite mitigating the risk of substantial downturns.  I request that you select a few new bio stocks, including SPRY, OTLK, and VTGN, and demonstrate how you would strategize for their upcoming PDUFA events.  To broaden your investment opportunities, I encourage you to also explore the po- tential impact of phase 2/3 trial results announcements.  This analysis must be firmly rooted in concrete evidence, devoid of conjecture. It is essential to illustrate the superiority of your strategy by leveraging all accessible information.  This requires conducting comprehensive testing and substantiating claims with empirical evidence.  For instance, demonstrating how investing in small-cap bio stocks ahead of anticipated PDUFA or phase 3 results announce- ments could have led to a significant AA% gain over a specified time interval of BB months using real examples.  Finally, you will craft an investment strategy tailored for the second half of 2024, focusing specifically on small bio stocks.  The maximum points allocated to this part of the presentation is 80.

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